Category Archives: Business Leader

Dr. Mikhail Blagosklonny’s significant contribution in the use of Rapamycin for treatment of various diseases.

Mikhail Blagosklonny is widely recognized for his extensive research on cancer. He is a professor at the Roswell Park Cancer Institute teaching oncology. He has held other positions prior to this in medicine. Mikhail worked at the Ordway Research Institute as a senior scientist and as an associate professor of medicine at the New York Medical College. He has advocated for the use of Rapamycin, an anti-aging drug for cancer patients. Rapamycin has many uses such as prevention of organ transplant rejection and a cancer drug. Its initial use was as an anti-fungal agent in the early years of discovery. However, there were discoveries on possession of more properties that could apply in treatment of other diseases. Mikhail has been in the forefront in conducting research on cancer therapies. He is committed to finding remedies to aging that has led to his advocacy in using rapamycin drug to increase human life span.

The drug has cited numerous benefits over time. It has immunosuppressant properties that make it very useful in organ transplants. While other drugs used to prevent organ rejection have adverse effects on the kidneys, rapamycin displays low toxicity on the kidneys. It is an excellent anti-rejection drug as identified in many research works. Due to its low toxicity towards the kidneys, the drug is also the best treatment for patients with hemolytic-uremic syndrome. This rare disease’s best treatment is through kidney transplant. It reduces the probability of the kidney contracting the disease after transplant. The benefits of rapamycin and its contribution towards longevity of life have been influential in Mikhail’s advocacy. Rapamycin is a cure for lymphangioleiomyomatosis that is a rare lung disease. It is also used as a coating of the coronary stents in order to prevent occurrence of re-stenosis. It has also been proven to reduce risks of cancer patients by enhancing immune responses of the body towards tumors.

Mikhail Blagosklonny has conducted research and tests to find out whether rapamycin increases longevity of humans. Initial tests on aging mice proved that the drug enhanced their ability to resist tuberculosis. He believes that the drug can increase human life span hence continues to conduct more research on the subject. Mikhail is in the process of conducting research to prove whether rapamycin can be an effective treatment for Alzheimer, muscular dystrophy and systemic lupus erythematous. He is also conducting research on the longevity of persons. Mikhail has taken keen interest in this area having conducted extensive research on aging. He conducted initial test on elderly patients by administering rapamycin before influenza vaccination that showed rejuvenation. However, it is not evident whether the drug increases longevity. He is committed to ensuring that all individuals are able to access the best treatment globally. Mikhail Blagosklonny is keen on finding out why cancer commonly affects individuals of a certain age group. He is interested in identifying the connection between age and cancer prevalence. He is dedicated to ensuring that treatment of cancer will be affordable to all individuals.

Eric Pulier Successfully Uses Technology to Make Lives Easier and Positively Impact on People Around Him

Eric Pulier is a successful individual, with numerous titles to his name. He is an entrepreneur, columnist, author, technologist, public speaker, and an active philanthropist. He attended the well-known Harvard University where he majored in English and American literature, graduating with a distinction.

 

Career

 

Eric Pulier’s brilliance started showing from an early age. He was doing computer programming at fourth grade and opened a database venture in high school. While at Harvard University, Eric was a columnist and an editor for Harvard Crimson. His first company was named People Doing Things, founded in 1994. The company focused on how technology can be used to improve everyday issues, such as education and healthcare. It later merged with US Interactive in 1998. Since then, Eric has not relented in creating more ventures that have been of help to many.

 

He has founded, co-founded and funded a number of start-ups mostly in technology, media, and capital funds. These companies include Digital Evolution, Media Platform, US Interactive, Akana, ServiceMesh, Desktone, and Enterprise Cloud Leadership Council among others. vAtomic Systems is the latest out of his sleeves. The firm focuses on building and improving a new technology named virtual atoms. This technology works in protecting private data saved in the cloud. Eric Pulier’s capabilities are nationally recognized. In 1997, the Presidential Inaugural Committee hired him for his outstanding skills to create the Presidential Technology Exhibition, which was named The Bridge to the 21st Century. His publications include Understanding Enterprise SOA, which he co-authored with Hugh Taylor and The Enterprise Industrial Complex.

 

Philanthropy

 

Eric Pulier has largely invested in the communities. Some of his most remarkable philanthropic startups include XPrize. He built this platform to award teens and youths who outdid themselves to reach to the top. These awards would work as a motivation to people who were rarely recognized. Eric Pulier has a passion for children with special needs. He has over the years donated money and his technological skills in creating platforms that help those children. Pulier played an integral role in establishing a camp dubbed the Painted Turtle for chronically ill children. He has also worked with Starbright World in creating an interaction media platform for children suffering from chronic diseases.